ABSTRACT
This case report describes three eyes of two patients, who were diagnosed to have endogenous fungal endophthalmitis post coronavirus disease 2019 (COVID-19) infection. Both patients underwent vitrectomy with intravitreal anti-fungal injection. Intra-ocular samples confirmed the fungal etiology by conventional microbiological investigations and polymerase chain reaction in both cases. The patients were treated with multiple intravitreal and oral anti-fungal agents; however, vision could not be salvaged.
Subject(s)
COVID-19 , Endophthalmitis , Eye Infections, Fungal , Humans , Eye Infections, Fungal/diagnosis , Eye Infections, Fungal/etiology , Eye Infections, Fungal/drug therapy , Endophthalmitis/diagnosis , Endophthalmitis/etiology , Endophthalmitis/drug therapy , Vitrectomy , Intravitreal Injections , Antifungal Agents/therapeutic use , Retrospective StudiesABSTRACT
A 13-year-old boy developed painless diminution of vision in left eye 15 days after taking first dose of coronavirus disease 2019 (COVID-19) vaccine (Corbevax). Fundus and fluorescein angiography revealed central retinal vein occlusion in the left eye. Blood investigations were noncontributory. He was administered three doses of pulse corticosteroids followed by a tapering dose of oral corticosteroids. Retinal vascular occlusion can occur following COVID-19 vaccination in children, and early and aggressive systemic anti-inflammatory therapy can be helpful.